Notoginsenoside R2, CAS [[80418-25-3]]

Produktübersicht

• Artikelname: Notoginsenoside R2, CAS [[80418-25-3]]
• Artikelnummer: MCE-HY-N0909
• Hersteller Artikelnummer: HY-N0909
• Alternativnummer: MCE-HY-N0909-10MG,MCE-HY-N0909-1MG,MCE-HY-N0909-5MG,MCE-HY-N0909-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 20(S)-Notoginsenoside R2, Ginsenoside Ng-R2

Produktbeschreibung

Notoginsenoside R2 (20(S)-Notoginsenoside R2, Ginsenoside Ng-R2) is an orally active notoginsenoside. Notoginsenoside R2 activates P90RSK and Nrf2 via the MEK1/2-ERK1/2 pathway to inhibit 6-OHDA-induced apoptotic damage in nerve cells. Notoginsenoside R2 upregulates SOX8/beta-catenin by reducing miR-27a, thereby suppressing Abeta25-35-induced neuronal apoptosis and inflammatory responses. Notoginsenoside R2 alleviates lipid accumulation and mitochondrial dysfunction in diabetic nephropathy by inhibiting c-Src. Notoginsenoside R2 alleviates hepatic fibrosis by inducing hepatic stellate cell senescence and inhibiting the inflammatory microenvironment via JAK/STAT3 suppression. Notoginsenoside R2 can be used in research related to Parkinsons disease, Alzheimers disease, diabetic nephropathy and hepatic fibrosis[1][2][3][4][5].

Produkteigenschaften

• Molekulargewicht: 770.99
• Reinheit: 99.80
• CAS Nummer: [80418-25-3]
• Formel: C41H70O13
• Target-Kategorie: Apoptosis,Caspase,COX,ERK,JAK,MDM-2/p53,MEK,Reactive Oxygen Species (ROS),Src,STAT,beta-catenin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products