Cudraflavone B, CAS [[19275-49-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N10009
Hersteller Artikelnummer:
HY-N10009
Alternativnummer:
MCE-HY-N10009-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Cudraflavone B is a prenylated flavonoid with anti-inflammatory and anti-tumor properties. Cudraflavone B is also a dual inhibitor of COX-1 and COX-2. Cudraflavone B blocks the translocation of nuclear factor kappaB (NF-kappaB) from the cytoplasm to the nucleus in macrophages. Thus, Cudraflavone B inhibits tumor necrosis factor alpha (TNFalpha) gene expression and secretion. Cudraflavone B also triggers the mitochondrial apoptotic pathway, activates NF-kappaB, the MAPK p38, and ERK, and induced the expression of SIRT1. Thus Cudraflavone B inhibits the growth of human oral squamous cell carcinoma cells[1][2].
Molekulargewicht:
420.45
CAS Nummer:
[19275-49-1]
Formel:
C25H24O6
Target-Kategorie:
COX,ERK,NF-kappaB,p38 MAPK,Sirtuin,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Natural Products
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