Cudraflavone B, CAS [[19275-49-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N10009
Supplier Catalog Number:
HY-N10009
Alternative Catalog Number:
MCE-HY-N10009-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Cudraflavone B is a prenylated flavonoid with anti-inflammatory and anti-tumor properties. Cudraflavone B is also a dual inhibitor of COX-1 and COX-2. Cudraflavone B blocks the translocation of nuclear factor kappaB (NF-kappaB) from the cytoplasm to the nucleus in macrophages. Thus, Cudraflavone B inhibits tumor necrosis factor alpha (TNFalpha) gene expression and secretion. Cudraflavone B also triggers the mitochondrial apoptotic pathway, activates NF-kappaB, the MAPK p38, and ERK, and induced the expression of SIRT1. Thus Cudraflavone B inhibits the growth of human oral squamous cell carcinoma cells[1][2].
Molecular Weight:
420.45
CAS Number:
[19275-49-1]
Formula:
C25H24O6
Target:
COX,ERK,NF-kappaB,p38 MAPK,Sirtuin,TNF Receptor
Application Notes:
MCE Product type: Natural Products
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