3-Oxo-cinobufagin, CAS [[6869-66-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N13081
Hersteller Artikelnummer:
HY-N13081
Alternativnummer:
MCE-HY-N13081-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagins cytotoxicity against cancer cells are: 71.3 µM (HepG2), 90.2 µM (SMMC-7221), 0.11 µM (BEL-7402), 72.5 µM (K562), 5.3 µM (HL-60), and 12 nM (HEL)[1].
Molekulargewicht:
440.53
CAS Nummer:
[6869-66-5]
Formel:
C26H32O6
Target-Kategorie:
Others
Anwendungsbeschreibung:
MCE Product type: Natural Products
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