3-Oxo-cinobufagin, CAS [[6869-66-5]] Preis auf Anfrage

Artikelnummer: MCE-HY-N13081
Artikelname: 3-Oxo-cinobufagin, CAS [[6869-66-5]] Preis auf Anfrage
Artikelnummer: MCE-HY-N13081
Hersteller Artikelnummer: HY-N13081
Alternativnummer: MCE-HY-N13081-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagins cytotoxicity against cancer cells are: 71.3 µM (HepG2), 90.2 µM (SMMC-7221), 0.11 µM (BEL-7402), 72.5 µM (K562), 5.3 µM (HL-60), and 12 nM (HEL)[1].
Molekulargewicht: 440.53
CAS Nummer: [6869-66-5]
Formel: C26H32O6
Target-Kategorie: Others
Anwendungsbeschreibung: MCE Product type: Natural Products