3-Oxo-cinobufagin, CAS [[6869-66-5]] Preis auf Anfrage

Product Overview

• Article Name: 3-Oxo-cinobufagin, CAS [[6869-66-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-N13081
• Supplier Catalog Number: HY-N13081
• Alternative Catalog Number: MCE-HY-N13081-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagins cytotoxicity against cancer cells are: 71.3 µM (HepG2), 90.2 µM (SMMC-7221), 0.11 µM (BEL-7402), 72.5 µM (K562), 5.3 µM (HL-60), and 12 nM (HEL)[1].

Product Properties

• Molecular Weight: 440.53
• CAS Number: [6869-66-5]
• Formula: C26H32O6
• Target: Others

Application Notes

• Application Notes: MCE Product type: Natural Products