Rhamnocitrin (Standard), CAS [[569-92-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: Rhamnocitrin (Standard), CAS [[569-92-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-N1353R
• Hersteller Artikelnummer: HY-N1353R
• Alternativnummer: MCE-HY-N1353R-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Rhamnocitrin (Standard) is the analytical standard of Rhamnocitrin. This product is intended for research and analytical applications. Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells)[1][2][3][4].

Produkteigenschaften

• Molekulargewicht: 300.26
• CAS Nummer: [569-92-6]
• Formel: C16H12O6
• Target-Kategorie: Others,p38 MAPK,Reference Standards

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference Standards