Rhamnocitrin (Standard), CAS [[569-92-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N1353R
Supplier Catalog Number:
HY-N1353R
Alternative Catalog Number:
MCE-HY-N1353R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Rhamnocitrin (Standard) is the analytical standard of Rhamnocitrin. This product is intended for research and analytical applications. Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells)[1][2][3][4].
Molecular Weight:
300.26
CAS Number:
[569-92-6]
Formula:
C16H12O6
Target:
Others,p38 MAPK,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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