Chrysosplenetin is one of the polymethoxylated flavonoids in Artemisia annua L. (Compositae) and other several Chinese herbs. Chrysosplenetin inhibits P-gp activity and reverses the up-regulated P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART, partially due to the uncompetitive inhibition effect of Chrysosplenetin on rat CYP3A[1].
Molekulargewicht:
374.34
Reinheit:
99.68
CAS Nummer:
[603-56-5]
Formel:
C19H18O8
Target-Kategorie:
Cytochrome P450,Ferroptosis,P-glycoprotein
Anwendungsbeschreibung:
MCE Product type: Natural Products
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