Americanin A, CAS [[69506-79-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-N18301
Hersteller Artikelnummer:
HY-N18301
Alternativnummer:
MCE-HY-N18301-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Americanin A is a neolignan. Americanin A can be isolated from the seeds of Phytolacca americana. Americanin A activates ATM and ATR, initiating the subsequent signal transduction cascades that include Chk1, Chk2, and tumor suppressor p53. Americanin A targets selectively Skp2 for degradation and thereby stabilizes p27. Americanin A suppresses the activity of Cyclin B1 and its partner cdc2 to prevent entry into Mitosis. Americanin A induces Apoptosis by producing excessive ROS. Americanin A has anti-cancer activity against colorectal cancer[1].
Molekulargewicht:
328.32
CAS Nummer:
[69506-79-2]
Formel:
C18H16O6
Target-Kategorie:
Apoptosis,ATM/ATR,CDK,Checkpoint Kinase (Chk),E1/E2/E3 Enzyme,MDM-2/p53,Mitosis,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Natural Products
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