Americanin A, CAS [[69506-79-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-N18301
Supplier Catalog Number:
HY-N18301
Alternative Catalog Number:
MCE-HY-N18301-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Americanin A is a neolignan. Americanin A can be isolated from the seeds of Phytolacca americana. Americanin A activates ATM and ATR, initiating the subsequent signal transduction cascades that include Chk1, Chk2, and tumor suppressor p53. Americanin A targets selectively Skp2 for degradation and thereby stabilizes p27. Americanin A suppresses the activity of Cyclin B1 and its partner cdc2 to prevent entry into Mitosis. Americanin A induces Apoptosis by producing excessive ROS. Americanin A has anti-cancer activity against colorectal cancer[1].
Molecular Weight:
328.32
CAS Number:
[69506-79-2]
Formula:
C18H16O6
Target:
Apoptosis,ATM/ATR,CDK,Checkpoint Kinase (Chk),E1/E2/E3 Enzyme,MDM-2/p53,Mitosis,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
* VAT and and shipping costs not included. Errors and price changes excepted
