p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate, Ethyl trans-4-hydroxycinnamate) is a non-competitive, reversible inhibitor of tyrosinase (IC50=4.89 µg/mL, Ki=1.83 µg/mL), which can quench the intrinsic fluorescence of the enzyme. p-Coumaric Acid Ethyl Ester changes the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain of tyrosinase, and does not bind to the copper ion of the enzyme. p-Coumaric Acid Ethyl Ester is used in the development of medicines, cosmetics and fruit preservation products using pollen[1].
Molekulargewicht:
192.21
Reinheit:
99.19
CAS Nummer:
[7362-39-2]
Formel:
C11H12O3
Target-Kategorie:
Tyrosinase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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