p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate, Ethyl trans-4-hydroxycinnamate) is a non-competitive, reversible inhibitor of tyrosinase (IC50=4.89 µg/mL, Ki=1.83 µg/mL), which can quench the intrinsic fluorescence of the enzyme. p-Coumaric Acid Ethyl Ester changes the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain of tyrosinase, and does not bind to the copper ion of the enzyme. p-Coumaric Acid Ethyl Ester is used in the development of medicines, cosmetics and fruit preservation products using pollen[1].
Molecular Weight:
192.21
Purity:
99.19
CAS Number:
[7362-39-2]
Formula:
C11H12O3
Target:
Tyrosinase
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
