Lotusine is an orally active signaling pathway modulator and enzyme inhibitor, with an IC50 of 30.60 µg/mL against alpha-amylase and an IC50 of 36.15 µg/mL against alpha-glucosidase. Lotusine inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR, Akt and ERK. Lotusine induces apoptosis, triggers G0/G1 cell cycle arrest and inhibits cancer cell proliferation. Lotusine reduces lipid peroxidation and increases the activities of SOD, CAT and GPx. Lotusine is applicable to researches related to non-small cell lung cancer, type 2 diabetes and autism spectrum disorder[1][2][3][4].
Molekulargewicht:
314.40
Reinheit:
99.91
CAS Nummer:
[6871-67-6]
Formel:
C19H24NO3
Target-Kategorie:
Amylases,Glycosidase
Anwendungsbeschreibung:
MCE Product type: Natural Products
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
