Flavanomarein is a substance with cytoprotective, anti-inflammatory and antioxidant activities, with a Ka of 3.064e-5 M against human Syk. Flavanomarein enhances the phosphorylation level of AKT, regulates the expression of PKC-delta, P85alpha, PKC-beta1, Sirt1, Bcl-2 and ICAD, and inhibits the nuclear translocation of NF-kappaB p65. Flavanomarein regulates EMT marker proteins, promotes the proliferation of HK-2 cells, and protects neuronal cells from 6-OHDA-induced neurotoxic damage. Flavanomarein can be used in studies related to Parkinsons disease and diabetic nephropathy.[1][2]
Molekulargewicht:
450.39
Reinheit:
99.92
CAS Nummer:
[577-38-8]
Formel:
C21H22O11
Target-Kategorie:
NF-kappaB,Syk,TGF-beta/Smad
Anwendungsbeschreibung:
MCE Product type: Natural Products
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten