Flavanomarein is a substance with cytoprotective, anti-inflammatory and antioxidant activities, with a Ka of 3.064e-5 M against human Syk. Flavanomarein enhances the phosphorylation level of AKT, regulates the expression of PKC-delta, P85alpha, PKC-beta1, Sirt1, Bcl-2 and ICAD, and inhibits the nuclear translocation of NF-kappaB p65. Flavanomarein regulates EMT marker proteins, promotes the proliferation of HK-2 cells, and protects neuronal cells from 6-OHDA-induced neurotoxic damage. Flavanomarein can be used in studies related to Parkinsons disease and diabetic nephropathy.[1][2]
Molecular Weight:
450.39
Purity:
99.92
CAS Number:
[577-38-8]
Formula:
C21H22O11
Target:
NF-kappaB,Syk,TGF-beta/Smad
Application Notes:
MCE Product type: Natural Products
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