Dehydromonocrotaline, CAS [[23291-96-5]]

Produktübersicht

• Artikelname: Dehydromonocrotaline, CAS [[23291-96-5]]
• Artikelnummer: MCE-HY-N9279
• Hersteller Artikelnummer: HY-N9279
• Alternativnummer: MCE-HY-N9279-5MG,MCE-HY-N9279-10MG,MCE-HY-N9279-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Monocrotaline pyrrole, MCTP, 3,8-Didehydromonocrotaline

Produktbeschreibung

Dehydromonocrotaline is a mitochondrial respiratory chain complex I NADH oxidase inhibitor, with a IC50 of 62.06 µM and a Ki of 8.1 µM in rats. Dehydromonocrotaline exerts non-competitive inhibitory effects by modifying cysteine thiol groups on complex I, and does not bind to the NADH-binding site. Dehydromonocrotaline dissipates mitochondrial membrane potential and reduces ATP levels. Dehydromonocrotaline can be used in studies related to hepatotoxicity, pulmonary hypertension and liver tumors[1][2][3].

Produkteigenschaften

• Molekulargewicht: 323.34
• CAS Nummer: [23291-96-5]
• Formel: C16H21NO6
• Target-Kategorie: Endogenous Metabolite

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products