beta-Sheet Breaker Peptide iAbeta5, CAS [[182912-74-9]]

Artikelnummer: MCE-HY-P1047
Artikelname: beta-Sheet Breaker Peptide iAbeta5, CAS [[182912-74-9]]
Artikelnummer: MCE-HY-P1047
Hersteller Artikelnummer: HY-P1047
Alternativnummer: MCE-HY-P1047-5MG,MCE-HY-P1047-10MG
Hersteller: MedchemExpress
Kategorie: Proteine/Peptide
Alternative Synonym: [Pro18, Asp21] beta-Amyloid (17-21)
beta-Sheet Breaker Peptide iAbeta5 is an effective brain amyloid-beta (Abeta) degrader. Abeta deposits are associated with Alzheimers disease (AD), and the related toxicity arises from its beta-sheet conformation and aggregation. beta-Sheet Breaker Peptide iAbeta5 can repeatedly induce the degradation of fibrillary amyloid deposits in vivo. Therefore, beta-Sheet Breaker Peptide iAbeta5 can prevent and/or reverse neuronal contraction caused by Abeta and reduce the range of interleukin IL-1beta positive microglial-like cells around Abeta deposits. beta-Sheet Breaker Peptide iAbeta5 can reduce the size and/or number of brain amyloid plaques in AD. beta-Sheet Breaker Peptide iAbeta5 is labeled with a hydrophobic benzyl alcohol (HBA) tag and shows a bright blue color under acidic conditions, which can be used for quantitative determination.
Molekulargewicht: 637.72
Reinheit: 99.92
CAS Nummer: [182912-74-9]
Formel: C33H43N5O8
Target-Kategorie: Amyloid-beta
Anwendungsbeschreibung: Peptides