Ac-DMLD-CMK, CAS [[2588354-33-8]] Preis auf Anfrage

Artikelnummer: MCE-HY-P10939
Artikelname: Ac-DMLD-CMK, CAS [[2588354-33-8]] Preis auf Anfrage
Artikelnummer: MCE-HY-P10939
Hersteller Artikelnummer: HY-P10939
Alternativnummer: MCE-HY-P10939-1UNIT
Hersteller: MedchemExpress
Kategorie: Proteine/Peptide
Ac-DmLD-CMK is a caspase 3 inhibitor and a GSDME inhibitor. Ac-DmLD-CMK binds directly to the catalytic domain of caspase-3, blocks caspase-3-mediated cleavage of GSDME, inhibits the activation of caspase 3 and Gsdme in the caspase 3-Gsdme signaling pathway, and reduces the levels of pyroptosis and apoptosis as well as the expression of LDH, IL-6, IL-1beta and IL-18. Ac-DmLD-CMK alleviates renal function deterioration, renal tubular epithelial cell injury, inflammatory cytokine secretion, pulmonary structural damage, and chemotherapy-induced nephrotoxicity[1][2][3].
Molekulargewicht: 567.05
CAS Nummer: [2588354-33-8]
Formel: C22H35ClN4O9S
Target-Kategorie: Caspase,Pyroptosis
Anwendungsbeschreibung: MCE Product type: Peptides