Ac-DMLD-CMK, CAS [[2588354-33-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P10939
Supplier Catalog Number:
HY-P10939
Alternative Catalog Number:
MCE-HY-P10939-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
Ac-DmLD-CMK is a caspase 3 inhibitor and a GSDME inhibitor. Ac-DmLD-CMK binds directly to the catalytic domain of caspase-3, blocks caspase-3-mediated cleavage of GSDME, inhibits the activation of caspase 3 and Gsdme in the caspase 3-Gsdme signaling pathway, and reduces the levels of pyroptosis and apoptosis as well as the expression of LDH, IL-6, IL-1beta and IL-18. Ac-DmLD-CMK alleviates renal function deterioration, renal tubular epithelial cell injury, inflammatory cytokine secretion, pulmonary structural damage, and chemotherapy-induced nephrotoxicity[1][2][3].
Molecular Weight:
567.05
CAS Number:
[2588354-33-8]
Formula:
C22H35ClN4O9S
Target:
Caspase,Pyroptosis
Application Notes:
MCE Product type: Peptides
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