Ac-DMLD-CMK, CAS [[2588354-33-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P10939
Supplier Catalog Number:
HY-P10939
Alternative Catalog Number:
MCE-HY-P10939-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
Ac-DMLD-CMK is a polypeptide targeting the mouse caspase 3-Gsdme signaling pathway. Ac-DMLD-CMK can specifically inhibit the activation of caspase 3 and Gsdme. Ac-DMLD-CMK blocks the cleavage of Gsdme by caspase 3, inhibits the occurrence of pyroptosis, thereby reducing renal tubular epithelial cell injury and the secretion of inflammatory cytokines. Ac-DMLD-CMK reduces the levels of serum creatinine and blood urea nitrogen in mice induced by Cisplatin (HY-17394) and alleviates the deterioration of kidney function. Ac-DMLD-CMK is promising for research of chemotherapy drug-induced nephrotoxicity[1].
Molecular Weight:
567.05
CAS Number:
[2588354-33-8]
Formula:
C22H35ClN4O9S
Target:
Caspase,Pyroptosis
Application Notes:
Peptides
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