P259 is a Drp1-Mff inhibitor. P259 distinguishes physiological from pathological fission by specifically inhibiting Drp1-Mff interaction. P259 elongates cell mitochondria and disrupts mitochondrial function and motility. P259 reduces ATP levels and alters mitochondrial structure in the brain, resulting in behavioral deficits in wild-type mice and a short lifespan in Huntingtons disease (HD) mice model[1].
Molekulargewicht:
1122.40
Reinheit:
99.75
Formel:
C54H95N11O14
Target-Kategorie:
ATP Synthase,Dynamin
Anwendungsbeschreibung:
Peptides
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