P259 is a Drp1-Mff inhibitor. P259 distinguishes physiological from pathological fission by specifically inhibiting Drp1-Mff interaction. P259 elongates cell mitochondria and disrupts mitochondrial function and motility. P259 reduces ATP levels and alters mitochondrial structure in the brain, resulting in behavioral deficits in wild-type mice and a short lifespan in Huntingtons disease (HD) mice model[1].
Molecular Weight:
1122.40
Purity:
99.75
Formula:
C54H95N11O14
Target:
ATP Synthase,Dynamin
Application Notes:
Peptides
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