(123B9)2-Motif is a selective EphA2 receptor agonist (Kd=4.9 µM) that does not bind to EphA4. (123B9)2-Motif works by inducing EphA2 receptor phosphorylation and oligomerization, thereby promoting receptor activation and internalization. (123B9)2-Motif is primarily used in targeted drug delivery studies for cancers that overexpress EphA2, such as breast cancer, to reduce circulating tumor cells and inhibit metastasis[1].
Molekulargewicht:
3199.17
Formel:
C142H197Cl2F2N31O47
Target-Kategorie:
Ephrin Receptor
Anwendungsbeschreibung:
Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
