(123B9)2-Motif is a selective EphA2 receptor agonist (Kd=4.9 µM) that does not bind to EphA4. (123B9)2-Motif works by inducing EphA2 receptor phosphorylation and oligomerization, thereby promoting receptor activation and internalization. (123B9)2-Motif is primarily used in targeted drug delivery studies for cancers that overexpress EphA2, such as breast cancer, to reduce circulating tumor cells and inhibit metastasis[1].
Molecular Weight:
3199.17
Formula:
C142H197Cl2F2N31O47
Target:
Ephrin Receptor
Application Notes:
Peptides
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