CIGB-552 TFA is a cell-penetrating peptide with anti-tumor properties with the IC50 of 23 µM in H460 cells. CIGB-552 TFA can increase the level of protein COMMD1. CIGB-552 TFA significantly inhibits the NF-kappaB signaling pathway. CIGB-552 TFA can promote apoptosis of the tumor cells. CIGB-552 TFA can induce the accumulation of reactive oxygen species (ROS) in tumor cells. CIGB-552 TFA has anti-inflammatory and anti-angiogenic effects. CIGB-552 TFA can be used for the research of the lung cancer and colon cancer[1][2][3][4].
Molekulargewicht:
2689.21 (free base)
Reinheit:
98.64
Formel:
C131H198N38O24xC2HF3O2
Target-Kategorie:
Apoptosis,NF-kappaB,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten