CIGB-552 TFA is a cell-penetrating peptide with anti-tumor properties with the IC50 of 23 µM in H460 cells. CIGB-552 TFA can increase the level of protein COMMD1. CIGB-552 TFA significantly inhibits the NF-kappaB signaling pathway. CIGB-552 TFA can promote apoptosis of the tumor cells. CIGB-552 TFA can induce the accumulation of reactive oxygen species (ROS) in tumor cells. CIGB-552 TFA has anti-inflammatory and anti-angiogenic effects. CIGB-552 TFA can be used for the research of the lung cancer and colon cancer[1][2][3][4].
Molecular Weight:
2689.21 (free base)
Purity:
98.64
Formula:
C131H198N38O24xC2HF3O2
Target:
Apoptosis,NF-kappaB,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Peptides
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