VMAPRTLFL is a 9-mer peptide derived from the signal peptide of HLA-G and can serve as a peptide ligand for HLA-E. VMAPRTLFL plays a crucial role in regulating the functions of adaptive natural killer (NK) cells. Specifically, VMAPRTLFL enriches FcepsilonRgamma- adaptive NK cells, upregulates the expression of CD25, and enhances their proliferative activity, antibody-dependent cellular cytotoxicity (ADCC), and IFN-gamma release. VMAPRTLFL can be used in research related to human cytomegalovirus (HCMV) infection, transplant rejection, and pregnancy immunity[1].
Molekulargewicht:
1047.31
CAS Nummer:
[202657-61-2]
Formel:
C49H82N12O11S
Target-Kategorie:
MHC
Anwendungsbeschreibung:
MCE Product type: Peptides
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