Guanidino-G-Clamp-PNA, CAS [[476667-31-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Guanidino-G-Clamp-PNA, CAS [[476667-31-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-P11698
• Hersteller Artikelnummer: HY-P11698
• Alternativnummer: MCE-HY-P11698-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide

Produktbeschreibung

Guanidino-G-Clamp-PNA is a highly efficient sequence-specific RNA binder and gene silencer. Guanidino-G-Clamp-PNA precisely targets such targets as miR-155 or transthyretin (TTR) mRNA through base pairing: the former regulates tumor-related signaling pathways by reducing microRNA activity, while the latter inhibits the translation of harmful proteins via steric hindrance. Guanidino-G-Clamp-PNA effectively stabilizes DNA/RNA duplexes, induces cancer cell apoptosis, and suppresses tumor growth. In addition, Guanidino-G-Clamp-PNA can be conjugated with targeting ligands to improve tissue-specific delivery and reduce in vivo adverse reactions, and it can also enhance the splicing regulation efficacy of other oligonucleotide platforms (such as PMO) when integrated into them. Guanidino-G-Clamp-PNA is applicable to the research of various diseases including diffuse large B-cell lymphoma and hereditary transthyretin-related amyloidosis[1][2].

Produkteigenschaften

• Molekulargewicht: 950.95
• CAS Nummer: [476667-31-9]
• Formel: C50H46N8O12
• Target-Kategorie: DNA Alkylator/Crosslinker,Transthyretin (TTR)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Peptides