PR-39, a natural proline- and arginine-rich antibacterial peptide, is a noncompetitive, reversible and allosteric proteasome inhibitor. PR-39 reversibly binds to the alpha7 subunit of the proteasome and blocks degradation of NF-kappaB inhibitor IkappaBalpha by the ubiquitin-proteasome pathway. PR-39 stimulates angiogenesis, inhibits inflammatory responses and significant reduces myocardial infarct size in mice[1][2].
Molekulargewicht:
4719.74
CAS Nummer:
[139637-11-9]
Formel:
C229H346N70O40
Target-Kategorie:
Bacterial,Proteasome
Anwendungsbeschreibung:
MCE Product type: Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
