Fz7-21 (TFA)

Artikelnummer: MCE-HY-P1454A
Artikelname: Fz7-21 (TFA)
Artikelnummer: MCE-HY-P1454A
Hersteller Artikelnummer: HY-P1454A
Alternativnummer: MCE-HY-P1454A-10MG,MCE-HY-P1454A-5MG,MCE-HY-P1454A-25MG
Hersteller: MedchemExpress
Kategorie: Proteine/Peptide
Alternative Synonym: Ac-LPSDDLEFWCHVMY-NH2 (TFA)
Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 TFA impairs the function of FZD7 in Wnt-beta-catenin signalling and stem cell function in intestinal organoids[1][2].
Molekulargewicht: 1910.07
Reinheit: 98.12
Formel: C85H115N18F3O25S2
Target-Kategorie: Wnt
Anwendungsbeschreibung: MCE Product type: Peptides