GO-203 (TFA), CAS [[1222186-26-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: GO-203 (TFA), CAS [[1222186-26-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-P1925A
• Hersteller Artikelnummer: HY-P1925A
• Alternativnummer: MCE-HY-P1925A-5MG,MCE-HY-P1925A-1MG,MCE-HY-P1925A-10MG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide

Produktbeschreibung

GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice[1][2].

Produkteigenschaften

• Molekulargewicht: 2426.77
• Reinheit: 99.28
• CAS Nummer: [1222186-26-6]
• Formel: C89H171F3N52O21S2
• Target-Kategorie: Apoptosis,PI3K,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Peptides