GO-203 (TFA), CAS [[1222186-26-6]] Preis auf Anfrage

Product Overview

• Article Name: GO-203 (TFA), CAS [[1222186-26-6]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-P1925A
• Supplier Catalog Number: HY-P1925A
• Alternative Catalog Number: MCE-HY-P1925A-5MG,MCE-HY-P1925A-1MG,MCE-HY-P1925A-10MG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide

Product Description

GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice[1][2].

Product Properties

• Molecular Weight: 2426.77
• Purity: 99.28
• CAS Number: [1222186-26-6]
• Formula: C89H171F3N52O21S2
• Target: Apoptosis,PI3K,Reactive Oxygen Species (ROS)

Application Notes

• Application Notes: MCE Product type: Peptides