TRV-120027, CAS [[1234510-46-3]]

Produktübersicht

• Artikelname: TRV-120027, CAS [[1234510-46-3]]
• Artikelnummer: MCE-HY-P2141
• Hersteller Artikelnummer: HY-P2141
• Alternativnummer: MCE-HY-P2141-1MG,MCE-HY-P2141-10MG,MCE-HY-P2141-5MG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: TRV027

Produktbeschreibung

TRV120027, a beta-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages beta-arrestins while blocking G-protein signaling[1]. TRV120027 induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling, promotes the formation of a macromolecular complex composed of AT1R-beta-arrestin-1-TRPC3-PLCgamma at the plasma membrane. TRV120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 has the potential for the acute decompensated heart failure (ADHF) treatment[2].

Produkteigenschaften

• Molekulargewicht: 926.07
• Reinheit: 98.2
• CAS Nummer: [1234510-46-3]
• Formel: C43H67N13O10
• Target-Kategorie: Angiotensin Receptor,Arrestin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Peptides