ELA-32(human) TFA is a potent, high affinity apelin receptor agonist (IC50=0.27 nM, Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFbeta pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
Molekulargewicht:
3967.82 (free acid)
Reinheit:
99.93
Formel:
C170H289N63O39S4.xC2HF3O2
Target-Kategorie:
Apelin Receptor (APJ)
Anwendungsbeschreibung:
MCE Product type: Peptides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
