Vm24-toxin, CAS [[1373890-79-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Vm24-toxin, CAS [[1373890-79-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-P5917
• Hersteller Artikelnummer: HY-P5917
• Alternativnummer: MCE-HY-P5917-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: Vaejovis mexicanus peptide 24

Produktbeschreibung

Vm24-toxin (Vaejovis mexicanus peptide 24), a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin folds into a distorted cystine-stabilized alpha/beta motif consisting of a single-turn alpha-helix and a three-stranded antiparallel beta-sheet, stabilized by four disulfide bridges. Vm24-toxin attenuates the CD4+ effector memory T cell response to T cell receptor (TCR) stimulation[1][2].

Produkteigenschaften

• Molekulargewicht: 3863.59
• CAS Nummer: [1373890-79-9]
• Formel: C157H253N51O45S9
• Target-Kategorie: Potassium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Peptides