Vm24-toxin, CAS [[1373890-79-9]] Preis auf Anfrage

Catalog Number: MCE-HY-P5917
Article Name: Vm24-toxin, CAS [[1373890-79-9]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-P5917
Supplier Catalog Number: HY-P5917
Alternative Catalog Number: MCE-HY-P5917-1UNIT
Manufacturer: MedchemExpress
Category: Proteine/Peptide
Alternative Names: Vaejovis mexicanus peptide 24
Vm24-toxin (Vaejovis mexicanus peptide 24), a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin folds into a distorted cystine-stabilized alpha/beta motif consisting of a single-turn alpha-helix and a three-stranded antiparallel beta-sheet, stabilized by four disulfide bridges. Vm24-toxin attenuates the CD4+ effector memory T cell response to T cell receptor (TCR) stimulation[1][2].
Molecular Weight: 3863.59
CAS Number: [1373890-79-9]
Formula: C157H253N51O45S9
Target: Potassium Channel
Application Notes: MCE Product type: Peptides