Animal-Free AITRL/TNFSF18, Human (His)

Produktübersicht

• Artikelname: Animal-Free AITRL/TNFSF18, Human (His)
• Artikelnummer: MCE-HY-P700014AF
• Hersteller Artikelnummer: HY-P700014AF
• Alternativnummer: MCE-HY-P700014AF-10UG,MCE-HY-P700014AF-2UG,MCE-HY-P700014AF-50UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: Animal-Free AITRL/TNFSF18 Protein, Human (His),Human,E. coli

Produktbeschreibung

AITRL, a type II transmembrane protein, is a ligand for glucocorticoid-induced TNFR-related protein (GITR). When AITRL binds to GITR, GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions. GITR/AITRL interaction plays a role in the pathogenesis of tumor, inflammation, as well as autoimmune diseases[1]. Besides, AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1, ICAM-1)[2]. Animal-Free AITRL/TNFSF18 Protein, Human (His) is a recombinant human AITRL (Q49-I174) with C-terminal His tag, which is expressed in E.coli.This product is for cell culture use only.

Produkteigenschaften

• Molekulargewicht: Approximately 11 kDa, based on SDS-PAGE under reducing conditions.
• Reinheit: 95
• Formel: 8995(Gene_ID)Q9UNG2 (Q49-I174)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins