Animal-Free AITRL/TNFSF18, Human (His)

Product Overview

• Article Name: Animal-Free AITRL/TNFSF18, Human (His)
• Biozol Catalog Number: MCE-HY-P700014AF
• Supplier Catalog Number: HY-P700014AF
• Alternative Catalog Number: MCE-HY-P700014AF-10UG,MCE-HY-P700014AF-2UG,MCE-HY-P700014AF-50UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: Animal-Free AITRL/TNFSF18 Protein, Human (His),Human,E. coli

Product Description

AITRL, a type II transmembrane protein, is a ligand for glucocorticoid-induced TNFR-related protein (GITR). When AITRL binds to GITR, GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions. GITR/AITRL interaction plays a role in the pathogenesis of tumor, inflammation, as well as autoimmune diseases[1]. Besides, AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1, ICAM-1)[2]. Animal-Free AITRL/TNFSF18 Protein, Human (His) is a recombinant human AITRL (Q49-I174) with C-terminal His tag, which is expressed in E.coli.This product is for cell culture use only.

Product Properties

• Molecular Weight: Approximately 11 kDa, based on SDS-PAGE under reducing conditions.
• Purity: 95
• Formula: 8995(Gene_ID)Q9UNG2 (Q49-I174)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins