Animal-Free BMP-3 Protein, Human (His),Human,E. coli
BMP-3 Protein, a TGF-beta superfamily member, crucially influences early skeletal formation and acts as a bone density negative regulator. It counteracts osteogenic BMPs, hindering osteoprogenitor differentiation. BMP-3 initiates signaling via ACVR2B, activating SMAD2-dependent and SMAD-independent pathways, including TAK1 and JNK. Structurally, it forms homodimers with disulfide bonds, interacting with ACVR2B to regulate functions. Animal-Free BMP-3 Protein, Human (His) is the recombinant human-derived animal-FreeBMP-3 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
Molekulargewicht:
Approximately 14 kDa, based on SDS-PAGE under reducing conditions.
Reinheit:
95
Formel:
651(Gene_ID)P12645 (Q363-R472)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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