Animal-Free BMP-3, Human (His)

Catalog Number: MCE-HY-P700026AF
Article Name: Animal-Free BMP-3, Human (His)
Biozol Catalog Number: MCE-HY-P700026AF
Supplier Catalog Number: HY-P700026AF
Alternative Catalog Number: MCE-HY-P700026AF-2UG,MCE-HY-P700026AF-10UG,MCE-HY-P700026AF-50UG
Manufacturer: MedchemExpress
Category: Proteine/Peptide
Alternative Names: Animal-Free BMP-3 Protein, Human (His),Human,E. coli
BMP-3 Protein, a TGF-beta superfamily member, crucially influences early skeletal formation and acts as a bone density negative regulator. It counteracts osteogenic BMPs, hindering osteoprogenitor differentiation. BMP-3 initiates signaling via ACVR2B, activating SMAD2-dependent and SMAD-independent pathways, including TAK1 and JNK. Structurally, it forms homodimers with disulfide bonds, interacting with ACVR2B to regulate functions. Animal-Free BMP-3 Protein, Human (His) is the recombinant human-derived animal-FreeBMP-3 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
Molecular Weight: Approximately 14 kDa, based on SDS-PAGE under reducing conditions.
Purity: 95
Formula: 651(Gene_ID)P12645 (Q363-R472)(Accession)
Application Notes: MCE Product type: Recombinant Proteins