BMP-2, Human/Mouse/Rat (Tag Free)

Produktübersicht

• Artikelname: BMP-2, Human/Mouse/Rat (Tag Free)
• Artikelnummer: MCE-HY-P7006B
• Hersteller Artikelnummer: HY-P7006B
• Alternativnummer: MCE-HY-P7006B-10UG,MCE-HY-P7006B-100UG,MCE-HY-P7006B-500UG,MCE-HY-P7006B-1MG,MCE-HY-P7006B-250UG,MCE-HY-P7006B-50UG,MCE-HY-P7006B-2UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: BMP-2 Protein, Human/Mouse/Rat (Tag Free),Rat,Mouse,Human,E. coli

Produktbeschreibung

Bone morphogenetic protein 2 (BMP-2) is a pleiotropic ligand protein belonging to TNFbeta family, and is involved in key embryonic development of vascular and valvular homeostasis. BMP-2 binds to type I receptors (ALK-2/-3/-6) and type II receptors (BMPR2, ACVR2A) to regulate various types of calcification, including atherosclerosis, chronic kidney disease, diabetes, and valve calcification[1]. BMP-2 is overexpressed by myofibroblast and preosteoblast in the calcified area of human calcified valve, which are densely infiltrated by B lymphocytes and T lymphocytes[2]. BMP-2 is the junction between atherosclerotic vascular calcification and normal bone formation mechanism[3]. BMP-2 Protein, Human/Mouse/Rat is 114 a.a. (Q283-R396), expressed in E. coli.

Produkteigenschaften

• Molekulargewicht: Approximately 13 kDa, based on SDS-PAGE under reducing conditions.
• Reinheit: 98.00
• Formel: 650(Gene_ID)P12643 (Q283-R396)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins