Fas/CD95, Human (HEK293, His)

Produktübersicht

• Artikelname: Fas/CD95, Human (HEK293, His)
• Artikelnummer: MCE-HY-P70329
• Hersteller Artikelnummer: HY-P70329
• Alternativnummer: MCE-HY-P70329-50UG,MCE-HY-P70329-10UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: Fas/CD95 Protein, Human (HEK293, His),Human,HEK293

Produktbeschreibung

Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD)[1][2]. Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-kappaB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases[3][4]. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, His) has a full length of 147 amino acids (Q26-N173), produced in HEK293 cells with C-terminal 6*His-tag.

Produkteigenschaften

• Molekulargewicht: 22-35 kDa
• Reinheit: 98
• Formel: 355(Gene_ID)P25445 (Q26-N173)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins