Fas/CD95, Human (HEK293, His)

Product Overview

• Article Name: Fas/CD95, Human (HEK293, His)
• Biozol Catalog Number: MCE-HY-P70329
• Supplier Catalog Number: HY-P70329
• Alternative Catalog Number: MCE-HY-P70329-50UG,MCE-HY-P70329-10UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: Fas/CD95 Protein, Human (HEK293, His),Human,HEK293

Product Description

Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD)[1][2]. Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-kappaB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases[3][4]. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, His) has a full length of 147 amino acids (Q26-N173), produced in HEK293 cells with C-terminal 6*His-tag.

Product Properties

• Molecular Weight: 22-35 kDa
• Purity: 98
• Formula: 355(Gene_ID)P25445 (Q26-N173)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins