Osteopontin/OPN, Human (HEK293, His)

Produktübersicht

• Artikelname: Osteopontin/OPN, Human (HEK293, His)
• Artikelnummer: MCE-HY-P70499
• Hersteller Artikelnummer: HY-P70499
• Alternativnummer: MCE-HY-P70499-100UG,MCE-HY-P70499-5UG,MCE-HY-P70499-50UG,MCE-HY-P70499-10UG,MCE-HY-P70499-1MG,MCE-HY-P70499-500UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: Osteopontin/OPN Protein, Human (HEK293, His),Human,HEK293

Produktbeschreibung

Osteopontin/OPN is a secretory glycophosphoprotein belonging to the SIBLING family. It contains RGD sequences and phosphorylation sites and can bind to integrins alphavbeta3, alpha4beta1 and CD44 receptors. Osteopontin/OPN regulates cell adhesion and migration through receptor-mediated regulation, activates MAPK/ERK and PI3K-AKT to promote tumor invasion, and upregulates TIMP-1/2 to inhibit MMPs and protect cartilage. Osteopontin/OPN can be used in the study of osteoarthritis, liver cancer, etc[1][2][3].

Produkteigenschaften

• Molekulargewicht: Approximately 55-70 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
• Reinheit: 98.00
• Formel: 6696(Gene_ID)P10451-1 (I17-N314)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins