Osteopontin/OPN Protein, Human (HEK293, His),Human,HEK293
Osteopontin/OPN is a secretory glycophosphoprotein belonging to the SIBLING family. It contains RGD sequences and phosphorylation sites and can bind to integrins alphavbeta3, alpha4beta1 and CD44 receptors. Osteopontin/OPN regulates cell adhesion and migration through receptor-mediated regulation, activates MAPK/ERK and PI3K-AKT to promote tumor invasion, and upregulates TIMP-1/2 to inhibit MMPs and protect cartilage. Osteopontin/OPN can be used in the study of osteoarthritis, liver cancer, etc[1][2][3].
Molecular Weight:
Approximately 55-70 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
98.00
Formula:
6696(Gene_ID)P10451-1 (I17-N314)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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