RSPO1/R-spondin-1, Human (CHO, His)

Produktübersicht

• Artikelname: RSPO1/R-spondin-1, Human (CHO, His)
• Artikelnummer: MCE-HY-P7114
• Hersteller Artikelnummer: HY-P7114
• Alternativnummer: MCE-HY-P7114-50UG,MCE-HY-P7114-100UG,MCE-HY-P7114-10UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: RSPO1/R-spondin-1 Protein, Human (CHO, His),Human,CHO

Produktbeschreibung

RSPO1/R-spondin-1 is a potent activator of the Wnt/beta-catenin signaling pathway and a secretory glycoprotein belonging to the R-spondin family. RSPO1 homotetramers synergize with LRP5/6 via LGR4/5/6 and activate the Wnt/beta-catenin pathway by inhibiting DKK1/Kremen-mediated LRP6 endocytosis. RSPO1 promotes beta-catenin nuclear translocation, drives HSC activation in liver fibrosis, inhibits adipocyte thermogenic gene expression, and promotes intestinal epithelial proliferation[1][2][3][4]. RSPO1/R-spondin-1 Protein, Human (CHO, His) is a recombinant human RSPO1 protein expressed in CHO cells with a C-6*His tag.

Produkteigenschaften

• Molekulargewicht: Approximately 38-43.3 kDa, based on SDS-PAGE under reducing conditions.
• Reinheit: 99.9
• Formel: 284654(Gene_ID)Q2MKA7-1 (S21-A263)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins