RSPO1/R-spondin-1, Human (CHO, His)

Product Overview

• Article Name: RSPO1/R-spondin-1, Human (CHO, His)
• Biozol Catalog Number: MCE-HY-P7114
• Supplier Catalog Number: HY-P7114
• Alternative Catalog Number: MCE-HY-P7114-50UG,MCE-HY-P7114-100UG,MCE-HY-P7114-10UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: RSPO1/R-spondin-1 Protein, Human (CHO, His),Human,CHO

Product Description

RSPO1/R-spondin-1 is a potent activator of the Wnt/beta-catenin signaling pathway and a secretory glycoprotein belonging to the R-spondin family. RSPO1 homotetramers synergize with LRP5/6 via LGR4/5/6 and activate the Wnt/beta-catenin pathway by inhibiting DKK1/Kremen-mediated LRP6 endocytosis. RSPO1 promotes beta-catenin nuclear translocation, drives HSC activation in liver fibrosis, inhibits adipocyte thermogenic gene expression, and promotes intestinal epithelial proliferation[1][2][3][4]. RSPO1/R-spondin-1 Protein, Human (CHO, His) is a recombinant human RSPO1 protein expressed in CHO cells with a C-6*His tag.

Product Properties

• Molecular Weight: Approximately 38-43.3 kDa, based on SDS-PAGE under reducing conditions.
• Purity: 99.9
• Formula: 284654(Gene_ID)Q2MKA7-1 (S21-A263)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins