Siglec-3/CD33 Protein, Human (HEK293, His),Human,HEK293
Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Human (HEK293, His) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-His labeled tag.
Molekulargewicht:
Approximately 40-46 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formel:
945(Gene_ID)AAH28152 (D18-H259)(Accession)
Anwendungsbeschreibung:
MCE Product type: Recombinant Proteins
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