Siglec-3/CD33, Human (HEK293, His)

Product Overview

• Article Name: Siglec-3/CD33, Human (HEK293, His)
• Biozol Catalog Number: MCE-HY-P73644
• Supplier Catalog Number: HY-P73644
• Alternative Catalog Number: MCE-HY-P73644-100UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: Siglec-3/CD33 Protein, Human (HEK293, His),Human,HEK293

Product Description

Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Human (HEK293, His) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-His labeled tag.

Product Properties

• Molecular Weight: Approximately 40-46 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
• Formula: 945(Gene_ID)AAH28152 (D18-H259)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins