USP5, Human (sf9, His, solution)

Produktübersicht

• Artikelname: USP5, Human (sf9, His, solution)
• Artikelnummer: MCE-HY-P74479Y
• Hersteller Artikelnummer: HY-P74479Y
• Alternativnummer: MCE-HY-P74479Y-20UG, MCE-HY-P74479Y-50UG
• Hersteller: MedchemExpress
• Kategorie: Proteine/Peptide
• Alternative Synonym: USP5 Protein, Human (sf9, His, solution),Human,Sf9 insect cells

Produktbeschreibung

USP5 protein selectively cleaves branched multiubiquitin polymers, favoring Lys-48-linked polyubiquitin disassembly. It exhibits lower affinity for linear and Lys-63-linked polyubiquitin. USP5 knockdown leads to p53/TP53 accumulation, enhancing p53/TP53 transcriptional activity, as unanchored polyubiquitin competes with ubiquitinated p53/TP53 for proteasomal recognition, unlike MDM2. USP5 Protein, Human (sf9, His, solution) is the recombinant human-derived USP5 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Produkteigenschaften

• Molekulargewicht: Approximately 85-94 kDa, based on SDS-PAGE under reducing conditions.
• Reinheit: 90
• Formel: 8078(Gene_ID)P45974-2 (M1-S835)(Accession)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Recombinant Proteins