USP5, Human (sf9, His, solution)

Product Overview

• Article Name: USP5, Human (sf9, His, solution)
• Biozol Catalog Number: MCE-HY-P74479Y
• Supplier Catalog Number: HY-P74479Y
• Alternative Catalog Number: MCE-HY-P74479Y-20UG, MCE-HY-P74479Y-50UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: USP5 Protein, Human (sf9, His, solution),Human,Sf9 insect cells

Product Description

USP5 protein selectively cleaves branched multiubiquitin polymers, favoring Lys-48-linked polyubiquitin disassembly. It exhibits lower affinity for linear and Lys-63-linked polyubiquitin. USP5 knockdown leads to p53/TP53 accumulation, enhancing p53/TP53 transcriptional activity, as unanchored polyubiquitin competes with ubiquitinated p53/TP53 for proteasomal recognition, unlike MDM2. USP5 Protein, Human (sf9, His, solution) is the recombinant human-derived USP5 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Product Properties

• Molecular Weight: Approximately 85-94 kDa, based on SDS-PAGE under reducing conditions.
• Purity: 90
• Formula: 8078(Gene_ID)P45974-2 (M1-S835)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins